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Methylation been discovered on a range of lysine residues in varied histones: K4 (using the single-letter amino-acid code for lysine), K9, K27, K36 and K79 in histone H3, legal K20 in histone H4, K59 in the globular domain of histone H4 2 and K26 of histone H1B three Several proteins responsible for the methylation of specific residues have been characterised, and all however one among these comprises a SET domain
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